Computational Systems Biology



Course name: Computational Systems Biology: Next generation experiment data analysis
Course ID: BIOS 426/826 - Section 001, Fall 2015
Instructor: Chi Zhang
Time: Tue/Thu 2:00 am - 3:15 pm
Classroom: BEAD 176
Office Hour: Tue/Thu 3:15 pm - 4:15 pm, BEAD N107

Some documents
Syllabus

Class Schedule:
Date Topics Notes and documents etc. HWs, Quizs, Exams
8/25, 8/27 Introduction Syllabus
NGS Lecture 1
NGS Lecture 2
HW1 due by 8/31 at 11:59PM
9/1, 9/3 NGS NGS Lecture 3
NGS Lecture 4
An example of a fastq file
example of QC results
9/8, 9/10 NGS de novo assembly NGS Lecture 5
NGS Lecture 6
HW2 due by 9/16 at 11:59PM
Solutions for HW2
Discussion
9/15, 9/17 NGS genome variations NGS Lecture 7
small genome assembly
NGS Lecture 8
9/22, 9/24 NGS aligners Introducation to R
NGS Lecture 9
HW3 due by 9/28 at 11:59PM
exp_dat.txt
9/29, 10/1 RNA-seq NGS Lecture 10
NGS Lecture 11: RNA-seq analysis
HW4 due by 10/5 at 11:59PM
refgenome.fa
50_reads.fastq
10/6, 10/8 Application of RNA-seq Lecture 12
Lecture 13: ChIP-seq
HW5 due by 10/12 at 11:59PM
RNA_seq_data.txt
10/13, 10/15 Microarray data analysis Lecture 14: Metagenomics
Microarray Lecture 1
HW6 due by 10/22 at 11:59PM
10/20 (fall break), 10/22 Microarray data analysis Fall Break
Microarray Lecture 2
You need to decide which paper you will present.
HW7 due by 11/1 at 11:59PM
10/27, 10/29 Transcriptome, GO databae and function annotation Transcriptome Lecture 1
Transcriptome Lecture 2
solutions for HW5
solutions for HW6
11/3, 11/5 Midterm Exam Transcriptome Lecture 3
No class on Thursday
Midterm Exam due by 11/11 at 11:59PM RNAseq_data_noreplicate.txt
RNA_seq_data.txt
11/10, 11/12 Graph theory Graph Theory Lecture 1
Graph Theory Lecture 2
HW8 igraph in R due by 11/19 at 11:59PM
graph.list
graph_windows.list
11/17, 11/19 PPI network PPI Lecture 1
PPI Lecture 2
HW9 due by 12/1 at 11:59PM
ATH_PPI.list
11/24, 11/26 (Thanksgiving) Student Presentation Baral, Daharsh, DasGupta, Du, Kesinger
12/1, 12/3 Student Presentation 12/1:Levine, Mao, Moore, Yang
12/3:Kumar, Mediratta, Payne, Ronish, Neal
12/8, 12/10 Gene network and Data integration Gene regulatory networks
Data integration
Final Exam Final exam due by Dec 14, 11:59PM

For more information please contact:

Chi Zhang
School of Biological Sciences
Center for Plant Science Innovation
Office: N107 Beadle
University of Nebraska-Lincoln
Lincoln, NE
Tel: 402-472-1396
Email: czhang5@unl.edu