Transcription Factor Family: MBF1
Tsuda et al. 2004: Multiprotein bridging factor 1 (MBF1) is known to be a transcriptional co-activator that mediates transcriptional activation by bridging between an activator and a TATA-box binding protein (TBP). We demonstrated that expression of every three MBF1 from Arabidopsis partially rescues the yeast mbf1 mutant phenotype, indicating that all of them function as co-activators for GCN4-dependent transcriptional activation. We also report that each of their subtypes shows distinct tissue-specific expression patterns and responses to phytohormones. These observations suggest that even though they share a similar biochemical function, each MBF1 has distinct roles in various tissues and conditions.
There are 3 transcription factors which have been predicted for 3D structure in this family:
| Transcription Factor ID | Gene Description |
| AT2G42680.1 | Description: MBF1A (MULTIPROTEIN BRIDGING FACTOR 1A); DNA binding / transcription coactivator; Organism: Arabidopsis thaliana; Chromosome: 2; GeneType: Protein Coding; NCBI gene id: 818868 |
| AT3G24500.1 | Description: MBF1C (MULTIPROTEIN BRIDGING FACTOR 1C); DNA binding / transcription coactivator/ transcription factor; Organism: Arabidopsis thaliana; Chromosome: 3; GeneType: Protein Coding; NCBI gene id: 822041 |
| AT3G58680.1 | Description: MBF1B (MULTIPROTEIN BRIDGING FACTOR 1B); DNA binding / transcription coactivator; Organism: Arabidopsis thaliana; Chromosome: 3; GeneType: Protein Coding; NCBI gene id: 825037 |