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Transcription Factor Family: AUX/IAA

Tiwari et al. 2004: Aux/IAA proteins are short-lived nuclear proteins that repress expression of primary/early auxin response genes in protoplast transfection assays. Repression is thought to result from Aux/IAA proteins dimerizing with auxin response factor (ARF) transcriptional activators that reside on auxin-responsive promoter elements, referred to as AuxREs. Most Aux/IAA proteins contain four conserved domains, designated domains I, II, III, and IV. Domain II and domains III and IV play roles in protein stability and dimerization, respectively. A clear function for domain I had not been established. Results reported here indicate that domain I in Aux/IAA proteins is an active repression domain that is transferable and dominant over activation domains. An LxLxL motif within domain I is important for conferring repression. The dominance of Aux/IAA repression domains over activation domains in ARF transcriptional activators provides a plausible explanation for the repression of auxin response genes via ARF-Aux/IAA dimerization on auxin-responsive promoters.

There are 27 transcription factors which have been predicted for 3D structure in this family:

Transcription Factor IDGene Description
AT1G04100.1Description:   IAA10; transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 1;  GeneType: Protein Coding;  NCBI gene id: 839290
AT1G04240.1Description:   SHY2 (SHORT HYPOCOTYL 2); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 1;  GeneType: Protein Coding;  NCBI gene id: 839570
AT1G04250.1Description:   AXR3 (AUXIN RESISTANT 3); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 1;  GeneType: Protein Coding;  NCBI gene id: 839568
AT1G04550.1Description:   IAA12 (AUXIN-INDUCED PROTEIN 12); transcription factor/ transcription repressor;  Organism: Arabidopsis thaliana;  Chromosome: 1;  GeneType: Protein Coding;  NCBI gene id: 839495
AT1G15050.1Description:   IAA34 (INDOLE-3-ACETIC ACID INDUCIBLE 34); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 1;  GeneType: Protein Coding;  NCBI gene id: 838070
AT1G15580.1Description:   IAA5 (INDOLE-3-ACETIC ACID INDUCIBLE 5); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 1;  GeneType: Protein Coding;  NCBI gene id: 838128
AT1G51950.1Description:   IAA18 (INDOLE-3-ACETIC ACID INDUCIBLE 18); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 1;  GeneType: Protein Coding;  NCBI gene id: 841623
AT1G52830.1Description:   IAA6 (INDOLE-3-ACETIC ACID 6); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 1;  GeneType: Protein Coding;  NCBI gene id: 841717
AT1G80390.1Description:   IAA15 (INDOLE-3-ACETIC ACID INDUCIBLE 15); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 1;  GeneType: Protein Coding;  NCBI gene id: 844379
AT2G22670.1Description:   IAA8; transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 2;  GeneType: Protein Coding;  NCBI gene id: 816798
AT2G33310.1Description:   IAA13; transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 2;  GeneType: Protein Coding;  NCBI gene id: 817894
AT2G46990.1Description:   IAA20 (INDOLE-3-ACETIC ACID INDUCIBLE 20); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 2;  GeneType: Protein Coding;  NCBI gene id: 819313
AT3G04730.1Description:   IAA16; transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 3;  GeneType: Protein Coding;  NCBI gene id: 819633
AT3G15540.1Description:   IAA19 (INDOLE-3-ACETIC ACID INDUCIBLE 19); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 3;  GeneType: Protein Coding;  NCBI gene id: 820793
AT3G16500.1Description:   PAP1 (PHYTOCHROME-ASSOCIATED PROTEIN 1); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 3;  GeneType: Protein Coding;  NCBI gene id: 820898
AT3G17600.1Description:   IAA31 (INDOLE-3-ACETIC ACID INDUCIBLE 31); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 3;  GeneType: Protein Coding;  NCBI gene id: 821026
AT3G23030.1Description:   IAA2 (INDOLE-3-ACETIC ACID INDUCIBLE 2); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 3;  GeneType: Protein Coding;  NCBI gene id: 821877
AT3G23050.1Description:   IAA7 (INDOLE-3-ACETIC ACID 7); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 3;  GeneType: Protein Coding;  NCBI gene id: 821879
AT3G62100.1Description:   IAA30 (INDOLE-3-ACETIC ACID INDUCIBLE 30); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 3;  GeneType: Protein Coding;  NCBI gene id: 825383
AT4G14550.1Description:   IAA14 (INDOLE-3-ACETIC ACID INDUCIBLE 14); protein binding / transcription factor/ transcription repressor;  Organism: Arabidopsis thaliana;  Chromosome: 4;  GeneType: Protein Coding;  NCBI gene id: 827102
AT4G14560.1Description:   IAA1 (INDOLE-3-ACETIC ACID INDUCIBLE); protein binding / transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 4;  GeneType: Protein Coding;  NCBI gene id: 827103
AT4G28640.1Description:   IAA11 (INDOLE-3-ACETIC ACID INDUCIBLE 11); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 4;  GeneType: Protein Coding;  NCBI gene id: 828982
AT4G29080.1Description:   PAP2 (PHYTOCHROME-ASSOCIATED PROTEIN 2); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 4;  GeneType: Protein Coding;  NCBI gene id: 829029
AT4G32280.1Description:   IAA29 (INDOLE-3-ACETIC ACID INDUCIBLE 29); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 4;  GeneType: Protein Coding;  NCBI gene id: 829361
AT5G25890.1Description:   IAA28 (INDOLE-3-ACETIC ACID INDUCIBLE 28); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 5;  GeneType: Protein Coding;  NCBI gene id: 832658
AT5G43700.1Description:   ATAUX2-11 (AUXIN INDUCIBLE 2-11); DNA binding / transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 5;  GeneType: Protein Coding;  NCBI gene id: 834390
AT5G65670.1Description:   IAA9 (INDOLE-3-ACETIC ACID INDUCIBLE 9); transcription factor;  Organism: Arabidopsis thaliana;  Chromosome: 5;  GeneType: Protein Coding;  NCBI gene id: 836693