Transcription Factor Family: SNF2
Eisen et al. 1995: The SNF2 family of proteins includes representatives from a variety of species with roles in cellular processes such as transcriptional regulation (e.g. MOT1, SNF2 and BRM), maintenance of chromosome stability during mitosis (e.g. lodestar) and various aspects of processing of DNA damage, including nucleotide excision repair (e.g. RAD16 and ERCC6), recombinational pathways (e.g. RAD54) and post-replication daughter strand gap repair (e.g. RAD5). This family also includes many proteins with no known function. To better characterize this family of proteins we have used molecular phylogenetic techniques to infer evolutionary relationships among the family members. We have divided the SNF2 family into multiple subfamilies, each of which represents what we propose to be a functionally and evolutionarily distinct group. We have then used the subfamily structure to predict the functions of some of the uncharacterized proteins in the SNF2 family. We discuss possible implications of this evolutionary analysis on the general properties and evolution of the SNF2 family.
There are 45 transcription factors which have been predicted for 3D structure in this family:
| Transcription Factor ID | Gene Description |
| AT1G02670.1 | Description: DNA repair protein, putative; Organism: Arabidopsis thaliana; Chromosome: 1; GeneType: Protein Coding; NCBI gene id: 839532 |
| AT1G03750.1 | Description: SWI2 (SWITCH 2); ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 1; GeneType: Protein Coding; NCBI gene id: 839417 |
| AT1G05120.1 | Description: SNF2 domain-containing protein / helicase domain-containing protein / RING finger domain-containing protein; Organism: Arabidopsis thaliana; Chromosome: 1; GeneType: Protein Coding; NCBI gene id: 839319 |
| AT1G05490.1 | Description: chr31 (chromatin remodeling 31); ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 1; GeneType: Protein Coding; NCBI gene id: 837051 |
| AT1G08600.1 | Description: ATRX; ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 1; GeneType: Protein Coding; NCBI gene id: 837382 |
| AT1G11100.1 | Description: SNF2 domain-containing protein / helicase domain-containing protein / zinc finger protein-related; Organism: Arabidopsis thaliana; Chromosome: 1; GeneType: Protein Coding; NCBI gene id: 837651 |
| AT1G48310.1 | Description: CHR18; ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 1; GeneType: Protein Coding; NCBI gene id: 841251 |
| AT1G50410.1 | Description: SNF2 domain-containing protein / helicase domain-containing protein / RING finger domain-containing protein; Organism: Arabidopsis thaliana; Chromosome: 1; GeneType: Protein Coding; NCBI gene id: 841463 |
| AT1G61140.1 | Description: EDA16 (embryo sac development arrest 16); ATP binding / DNA binding / helicase/ nucleic acid binding / protein binding / zinc ion binding; Organism: Arabidopsis thaliana; Chromosome: 1; GeneType: Protein Coding; NCBI gene id: 842407 |
| AT1G61140.2 | Description: EDA16 (embryo sac development arrest 16); ATP binding / DNA binding / helicase/ nucleic acid binding / protein binding / zinc ion binding; Organism: Arabidopsis thaliana; Chromosome: 1; GeneType: Protein Coding; NCBI gene id: 842407 |
| AT1G61140.3 | Description: EDA16 (embryo sac development arrest 16); ATP binding / DNA binding / helicase/ nucleic acid binding / protein binding / zinc ion binding; Organism: Arabidopsis thaliana; Chromosome: 1; GeneType: Protein Coding; NCBI gene id: 842407 |
| AT2G02090.1 | Description: ETL1; ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 2; GeneType: Protein Coding; NCBI gene id: 814740 |
| AT2G13370.1 | Description: CHR5 (chromatin remodeling 5); ATP binding / DNA binding / chromatin binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 2; GeneType: Protein Coding; NCBI gene id: 815823 |
| AT2G16390.1 | Description: DRD1 (DEFECTIVE IN RNA-DIRECTED DNA METHYLATION 1); ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 2; GeneType: Protein Coding; NCBI gene id: 816136 |
| AT2G18760.1 | Description: CHR8 (chromatin remodeling 8); ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 2; GeneType: Protein Coding; NCBI gene id: 816391 |
| AT2G21450.1 | Description: CHR34 (chromatin remodeling 34); ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 2; GeneType: Protein Coding; NCBI gene id: 816684 |
| AT2G28290.1 | Description: SYD (SPLAYED); ATPase/ chromatin binding; Organism: Arabidopsis thaliana; Chromosome: 2; GeneType: Protein Coding; NCBI gene id: 817375 |
| AT2G28290.2 | Description: SYD (SPLAYED); ATPase/ chromatin binding; Organism: Arabidopsis thaliana; Chromosome: 2; GeneType: Protein Coding; NCBI gene id: 817375 |
| AT2G28290.3 | Description: SYD (SPLAYED); ATPase/ chromatin binding; Organism: Arabidopsis thaliana; Chromosome: 2; GeneType: Protein Coding; NCBI gene id: 817375 |
| AT2G44980.1 | Description: transcription regulatory protein SNF2, putative; Organism: Arabidopsis thaliana; Chromosome: 2; GeneType: Protein Coding; NCBI gene id: 819106 |
| AT2G44980.2 | Description: transcription regulatory protein SNF2, putative; Organism: Arabidopsis thaliana; Chromosome: 2; GeneType: Protein Coding; NCBI gene id: 819106 |
| AT2G46020.1 | Description: transcription regulatory protein SNF2, putative; Organism: Arabidopsis thaliana; Chromosome: 2; GeneType: Protein Coding; NCBI gene id: 819210 |
| AT2G46020.2 | Description: transcription regulatory protein SNF2, putative; Organism: Arabidopsis thaliana; Chromosome: 2; GeneType: Protein Coding; NCBI gene id: 819210 |
| AT3G06010.1 | Description: ATCHR12; ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 3; GeneType: Protein Coding; NCBI gene id: 819772 |
| AT3G06400.1 | Description: CHR11 (CHROMATIN-REMODELING PROTEIN 11); ATP binding / DNA binding / DNA-dependent ATPase/ helicase/ hydrolase, acting on acid anhydrides, in phosphorus-containing anhydrides / nucleic acid binding / nucleosome binding; Organism: Arabidopsis thaliana; Chromosome: 3; GeneType: Protein Coding; NCBI gene id: 819814 |
| AT3G12810.1 | Description: PIE1 (PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1); ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 3; GeneType: Protein Coding; NCBI gene id: 820463 |
| AT3G16600.1 | Description: SNF2 domain-containing protein / helicase domain-containing protein / RING finger domain-containing protein; Organism: Arabidopsis thaliana; Chromosome: 3; GeneType: Protein Coding; NCBI gene id: 820911 |
| AT3G19210.1 | Description: ATRAD54 (ARABIDOPSIS HOMOLOG OF RAD54); ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 3; GeneType: Protein Coding; NCBI gene id: 821455 |
| AT3G20010.1 | Description: SNF2 domain-containing protein / helicase domain-containing protein / RING finger domain-containing protein; Organism: Arabidopsis thaliana; Chromosome: 3; GeneType: Protein Coding; NCBI gene id: 821539 |
| AT3G24340.1 | Description: chr40 (chromatin remodeling 40); ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 3; GeneType: Protein Coding; NCBI gene id: 822023 |
| AT3G42670.1 | Description: CHR38 (CHROMATIN REMODELING 38); ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 3; GeneType: Protein Coding; NCBI gene id: 823287 |
| AT3G54280.1 | Description: RGD3 (ROOT GROWTH DEFECTIVE 3); ATP binding / DNA binding / binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 3; GeneType: Protein Coding; NCBI gene id: 824595 |
| AT3G54460.1 | Description: SNF2 domain-containing protein / helicase domain-containing protein / F-box family protein; Organism: Arabidopsis thaliana; Chromosome: 3; GeneType: Protein Coding; NCBI gene id: 824611 |
| AT3G57300.1 | Description: INO80 (INO80 ORTHOLOG); ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 3; GeneType: Protein Coding; NCBI gene id: 824897 |
| AT4G31900.1 | Description: chromatin remodeling factor, putative; Organism: Arabidopsis thaliana; Chromosome: 4; GeneType: Protein Coding; NCBI gene id: 829320 |
| AT5G05130.1 | Description: SNF2 domain-containing protein / helicase domain-containing protein / RING finger domain-containing protein; Organism: Arabidopsis thaliana; Chromosome: 5; GeneType: Protein Coding; NCBI gene id: 830395 |
| AT5G07810.1 | Description: SNF2 domain-containing protein / helicase domain-containing protein / HNH endonuclease domain-containing protein; Organism: Arabidopsis thaliana; Chromosome: 5; GeneType: Protein Coding; NCBI gene id: 830674 |
| AT5G18620.1 | Description: CHR17 (CHROMATIN REMODELING FACTOR17); ATP binding / DNA binding / DNA-dependent ATPase/ helicase/ hydrolase, acting on acid anhydrides, in phosphorus-containing anhydrides / nucleic acid binding / nucleosome binding; Organism: Arabidopsis thaliana; Chromosome: 5; GeneType: Protein Coding; NCBI gene id: 831980 |
| AT5G18620.2 | Description: CHR17 (CHROMATIN REMODELING FACTOR17); ATP binding / DNA binding / DNA-dependent ATPase/ helicase/ hydrolase, acting on acid anhydrides, in phosphorus-containing anhydrides / nucleic acid binding / nucleosome binding; Organism: Arabidopsis thaliana; Chromosome: 5; GeneType: Protein Coding; NCBI gene id: 831980 |
| AT5G19310.1 | Description: homeotic gene regulator, putative; Organism: Arabidopsis thaliana; Chromosome: 5; GeneType: Protein Coding; NCBI gene id: 832051 |
| AT5G20420.1 | Description: CHR42 (chromatin remodeling 42); ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 5; GeneType: Protein Coding; NCBI gene id: 832164 |
| AT5G22750.1 | Description: RAD5; ATP binding / ATP-dependent helicase/ DNA binding / helicase/ hydrolase, acting on acid anhydrides, in phosphorus-containing anhydrides / nucleic acid binding / protein binding / zinc ion binding; Organism: Arabidopsis thaliana; Chromosome: 5; GeneType: Protein Coding; NCBI gene id: 832338 |
| AT5G43530.1 | Description: SNF2 domain-containing protein / helicase domain-containing protein / RING finger domain-containing protein; Organism: Arabidopsis thaliana; Chromosome: 5; GeneType: Protein Coding; NCBI gene id: 834373 |
| AT5G63950.1 | Description: CHR24 (chromatin remodeling 24); ATP binding / DNA binding / helicase/ nucleic acid binding; Organism: Arabidopsis thaliana; Chromosome: 5; GeneType: Protein Coding; NCBI gene id: 836516 |
| AT5G66750.1 | Description: CHR1 (CHROMATIN REMODELING 1); ATPase/ helicase; Organism: Arabidopsis thaliana; Chromosome: 5; GeneType: Protein Coding; NCBI gene id: 836808 |